26 May Local Anesthetics and Covid19 Associated Acute Respiratory Distress Syndrome: A New Therapeutic Indication? Clinical Research:Open Access Vol 6 (2): 1-5 2020
Today is an important day. It is an important day for the integrative way of thinking in medicine, it is an important day for bio-logical medicine, it is an important day for me, and I hope, it will soon proved to be an important day for the struggle against Covid19 pandemic. My article “ Local Anesthetics and Covid19 Associated Acute Respiratory Distress Syndrome: A New therapeutic Indication” gets today in public. The way now for clinical trials using a cheap, miraculous, but underestimated drug like a local anesthetic treating various inflammatory conditions lies open ahead. This article belongs to the group of the so called “review articles”, but it is far more than that for two reasons. First because it focus the attention not in the pathogen causing a disease, but on the functional state of the tissue where infection and the subsequent inflammation take place. It is said that Louis Pasteur, the father of the germ theory of disease recognized this fact on his deathbed by saying “The microbe is nothing, the terrain is everything”. I was inspired by these words while I was working hard on it during the lockdown phase. I was also aware of the words which another giant of Medicine, Claude Bernard, once said: “It is what we know already that often prevents us from learning”. But still, progress comes with innovation, and “out of the box” thinking. And when new ideas find substantial support by the findings of current science, then a possible practical solution can be offered. And this exactly is the second reason why this review is not just a review. To bring these ideas and thoughts into a form it is not something that occurs serendipitously. Looking back in twenty years of experience with the therapeutic use of local anesthetics and eleven years since the foundation of the Hellenic Society of Neural Therapy and Study of Homeostasis it becomes obvious for me under which circumstances my thoughts got fertilized. These ideas were also submitted to the Pan-European Hackathon, EU vs Virus. I want to thank the editorial board of the Clinical Research: Open Access Journal and also the reviewers about their comments on the quality of my work. Today is an important day.
The article can be retrieved online under:
https://www.sciforschenonline.org/journals/clinical-research/CLROA156.php
https://www.sciforschenonline.org/journals/clinical-research/article-data/CLROA156/CLROA156.pdf
Dr.Gerasimos S. Papathanasiou DMD, PhD